Product Data Sheet

WIN 55,212-2 mesylate

Catalog No. A11932

main product photo
WIN 55,212-2 is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling.
Adooq's WIN 55,212-2 mesylate has been cited by 1 publications
  • Greish K, .et al. , J Control Release, 2018, Dec 10;291:184-195 PMID: 30367922
  • Chemical Information
    Catalog Num A11932
    M. Wt 522.6
    Formula C27H26N2O3.CH3SO3H
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 131543-23-2
    Synonyms (R)-(+)-WIN 55212
    SMILES CC1=C(C2=C3N1[C@@H](COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65.CS(=O)(=O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription WIN 55,212-2 is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling.
    Solubility
    In vitro DMSO 90 mg/mL (172.21 mM)
    Water 90 mg/mL (172.21 mM)
    Ethanol 18 mg/mL (34.43 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.14 mL 95.68 mL 191.35 mL
    0.5 mM 3.83 mL 19.14 mL 38.27 mL
    1 mM 1.91 mL 9.57 mL 19.14 mL
    5 mM 0.38 mL 1.91 mL 3.83 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.