Product Data Sheet

(Z)-SMI-4a

Catalog No. A11945

main product photo
SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. Mostly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.
Adooq's (Z)-SMI-4a has been cited by 1 publications
  • Liong S, .et al. , Placenta, 2017, May;53:101-112 PMID: 28487013
  • Chemical Information
    Catalog NumA11945
    M. Wt273.2
    FormulaC11H6F3NO2S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.327033-36-3
    SynonymsSMI4a
    SMILESO=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2
    Biological Activity
    DescriptionSIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. Mostly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.
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