Product Data Sheet

Dorsomorphin (BML-275)

Catalog No. A11970

main product photo
BML-275 is a cell-permeable pyrazolopyrimidine compound shown to be an AMP-activated protein kinase (AMPK) and fatty acid synthase inhibitor.
Adooq's Dorsomorphin (BML-275) has been cited by 4 publications
  • Yinhua Ni, .et al. , J Agric Food Chem, 2024, Jul 31;72(30):16708-16725 PMID: 39016108
  • Yinhua Ni, .et al. , J Nutr Biochem, 2024, Mar:125:109569 PMID: 38185346
  • Yu-Ting Chen, .et al. , World Neurosurg, 2023, Dec:180:e350-e363 PMID: 37757945
  • Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
  • Chemical Information
    Catalog NumA11970
    M. Wt399.5
    FormulaC24H25N5O
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.866405-64-3
    SynonymsBML275, BML 275
    SMILESC1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
    Biological Activity
    DescriptionBML-275 is a cell-permeable pyrazolopyrimidine compound shown to be an AMP-activated protein kinase (AMPK) and fatty acid synthase inhibitor.
    Targets
    TargetValue
    Solubility
    In vitro DMSOWarmed: 1 mg/mL (2.5 mM)
    WaterInsoluble
    EthanolWarmed: 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM25.03 mL125.16 mL250.31 mL
    0.5 mM5.01 mL25.03 mL50.06 mL
    1 mM2.5 mL12.52 mL25.03 mL
    5 mM0.5 mL2.5 mL5.01 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.