Product Data Sheet

VU 0364770

Catalog No. A12139

main product photo
VU 0364770 is a positive allosteric modulator at mGlu4 receptors with EC50 value of 290 nM in mGlu4-expressing HEK 293 cells.
Chemical Information
Catalog Num A12139
M. Wt 232.67
Formula C12H9ClN2O
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 61350-00-3
Synonyms VU0364770
SMILES C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription VU 0364770 is a positive allosteric modulator at mGlu4 receptors with EC50 value of 290 nM in mGlu4-expressing HEK 293 cells.
Targets
Target Value
Solubility
In vitro DMSO 46 mg/mL (197.7 mM)
Water Insoluble
Ethanol 46 mg/mL (197.7 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 42.98 mL 214.9 mL 429.79 mL
0.5 mM 8.6 mL 42.98 mL 85.96 mL
1 mM 4.3 mL 21.49 mL 42.98 mL
5 mM 0.86 mL 4.3 mL 8.6 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.