Product Data Sheet

Cilengitide

Catalog No. A12372

main product photo
Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
Adooq's Cilengitide has been cited by 6 publications
  • Marion Bouvet, .et al. , Sci Rep, 2020, 10: 11404 PMID: 32647159
  • Rosalie Richards, .et al. , bioRxiv, 2018, 15 Oct 2018
  • Hiroki Kanazawa, .et al. , PLoS One, 2017, 12(2): e0173051 PMID: 28235037
  • Yasuda J, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2017, Nov;390(11):1135-1144 PMID: 28785775
  • Yasuda J, .et al. , Eur J Pharmacol, 2017, Jul 15;807:64-70 PMID: 28457922
  • Hsian-Yu Wang, .et al. , Onco Targets Ther, 2016, 9: 2961-2973 PMID: 27284246
  • Chemical Information
    Catalog NumA12372
    M. Wt588.66
    FormulaC27H40N8O7
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.188968-51-6
    SynonymsEMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
    SMILESCC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N
    Biological Activity
    DescriptionCilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
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    SHIPPING AND STORAGE
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