Product Data Sheet

Verteporfin

Catalog No. A12658

main product photo

Verteporfin is a small molecule that inhibits TEAD, YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

Adooq's Verteporfin has been cited by 7 publications
  • Szonja Anna Kovács, .et al. , British Journal ofPharmacology, 2025, 05 May
  • Shruti Vig, .et al. , Cancer Drug Resist, 2024, Sep 21:7:35 PMID: 39403604
  • Yu Ren, .et al. , Eur J Med Res, 2024, May 30;29(1):303 PMID: 38812041
  • Po-Ju Lee, .et al. , J Exp Clin Cancer Res, 2022, Aug 20;41(1):254 PMID: 35986369
  • Ling-Yan Liu, .et al. , Int J Mol Med, 2020, Dec;46(6):2235-2250 PMID: 33125123
  • Wang Y, .et al. , Toxicol Appl Pharmacol, 2019, 2019 Dec 5;387:114852 PMID: 31812773
  • Abe T, .et al. , Toxicol Sci, 2018, Oct 1;165(2):408-419 PMID: 29893953
  • Chemical Information
    Catalog NumA12658
    M. Wt718.79
    FormulaC41H42N4O8
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.129497-78-5
    SynonymsVisudyne, DB00460, CL 318,952, Benzoporphyrin D, Bpd-MA, AIDS350621, AIDS-350621, Benzoporphyrin derivative monoacid ring A.
    SMILESO=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[C@]6(C)[C@H](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5
    Biological Activity
    Description

    Verteporfin is a small molecule that inhibits TEAD, YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

    Targets
    TargetValue
    Solubility
    In vitro DMSO89 mg/mL (123.82 mM)
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM13.91 mL69.56 mL139.12 mL
    0.5 mM2.78 mL13.91 mL27.82 mL
    1 mM1.39 mL6.96 mL13.91 mL
    5 mM0.28 mL1.39 mL2.78 mL
    RETURN POLICY
    Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.