Product Data Sheet

JNJ7777120

Catalog No. A12713

main product photo
JNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.
Adooq's JNJ7777120 has been cited by 2 publications
  • K Yamamoto, .et al. , Naunyn-Schmiedeberg's Arch Pharmacol, 2019, pp 1-12 PMID: 30919010
  • Yamamoto K, .et al. , Neurosci Lett, 2018, May 29;676:103-107 PMID: 29655943
  • Chemical Information
    Catalog NumA12713
    M. Wt277.75
    FormulaC14H16N3OCl
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.459168-41-3
    SynonymsJNJ 7777120, JNJ-7777120
    SMILESCN1CCN(CC1)C(=O)C2=CC3=C(N2)C=CC(=C3)Cl
    Biological Activity
    DescriptionJNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO49 mg/mL (176.42 mM)
    WaterInsoluble
    Ethanol7 mg/mL (25.2 mM)
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 19 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM36 mL180.02 mL360.04 mL
    0.5 mM7.2 mL36 mL72.01 mL
    1 mM3.6 mL18 mL36 mL
    5 mM0.72 mL3.6 mL7.2 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.