Product Data Sheet

Birinapant (TL32711)

Catalog No. A12738

main product photo
Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
Adooq's Birinapant (TL32711) has been cited by 1 publications
  • Antonella Antignani, .et al. , FASEB J, 2023, Dec;37(12):e23292 PMID: 37971407
  • Chemical Information
    Catalog NumA12738
    M. Wt806.94
    FormulaC42H56F2N8O6
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1260251-31-7
    SynonymsTL-32711, TL 32711
    SMILESCC[C@@H](C(=O)N1C[C@H](C[C@H]1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)C[C@@H]6C[C@@H](CN6C(=O)[C@H](CC)NC(=O)[C@H](C)NC)O)O)NC(=O)[C@H](C)NC
    Biological Activity
    DescriptionBirinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
    Targets
    TargetValue
    Solubility
    In vitro DMSO87 mg/mL (107.81 mM)
    WaterInsoluble
    Ethanol48 mg/mL (59.48 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM12.39 mL61.96 mL123.92 mL
    0.5 mM2.48 mL12.39 mL24.78 mL
    1 mM1.24 mL6.2 mL12.39 mL
    5 mM0.25 mL1.24 mL2.48 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.