Product Data Sheet

PF-04880594

Catalog No. A12739

main product photo
PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.
Chemical Information
Catalog NumA12739
M. Wt394.38
FormulaC19H16F2N8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1111636-35-1
SynonymsPF-04880594, PF04880594, PF 04880594
SMILESC1=CNC2=NC=C(C=C21)C3=NN(C=C3C4=NC(=NC=C4)NCCC#N)CC(F)F
Biological Activity
DescriptionPF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.
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