Product Data Sheet

NU7026

Catalog No. A12752

main product photo
NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
Adooq's NU7026 has been cited by 2 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Velichko AK, .et al. , Nucleic Acids Res, 2019, May 22. pii: gkz436 PMID: 31114877
  • Chemical Information
    Catalog NumA12752
    M. Wt281.31
    FormulaC17H15NO3
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.154447-35-5
    SynonymsNU 7026, NU-7026
    SMILESC1COCCN1C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3
    Biological Activity
    DescriptionNU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO1 mg/mL (3.55 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM35.55 mL177.74 mL355.48 mL
    0.5 mM7.11 mL35.55 mL71.1 mL
    1 mM3.55 mL17.77 mL35.55 mL
    5 mM0.71 mL3.55 mL7.11 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.