Product Data Sheet

PS-1145

Catalog No. A12789

main product photo
PS-1145 is a highly specific IKB kinase (IKK) inhibitor that efficiently inhibits both basal and induced NF-kB activity in PC cells.
Chemical Information
Catalog Num A12789
M. Wt 322.75
Formula C17H11ClN4O
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 431898-65-6
Synonyms PS1145,PS 1145
SMILES C1=CC(=CN=C1)C(=O)NC2=C3C(=CC(=C2)Cl)C4=C(N3)C=NC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription PS-1145 is a highly specific IKB kinase (IKK) inhibitor that efficiently inhibits both basal and induced NF-kB activity in PC cells.
Targets
Target Value
Solubility
In vitro DMSO 61 mg/mL (189 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (6.19 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.98 mL 154.92 mL 309.84 mL
0.5 mM 6.2 mL 30.98 mL 61.97 mL
1 mM 3.1 mL 15.49 mL 30.98 mL
5 mM 0.62 mL 3.1 mL 6.2 mL
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.