Product Data Sheet

HSP-990

Catalog No. A12850

main product photo
HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
Adooq's HSP-990 has been cited by 1 publications
  • Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422
  • Chemical Information
    Catalog NumA12850
    M. Wt379.39
    FormulaC20H18FN5O2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.934343-74-5
    SynonymsHSP990, HSP 990, NVP-HSP990
    SMILESCC1=NC(=NC2=C1C(=O)N[C@H](C2)C3=C(C=C(C=C3)F)C4=NC(=CC=C4)OC)N
    Biological Activity
    DescriptionHSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
    Targets
    TargetValue
    Solubility
    In vitro DMSO65 mg/mL (171.32 mM)
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM26.36 mL131.79 mL263.58 mL
    0.5 mM5.27 mL26.36 mL52.72 mL
    1 mM2.64 mL13.18 mL26.36 mL
    5 mM0.53 mL2.64 mL5.27 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.