Product Data Sheet

HSP-990

Catalog No. A12850

main product photo
HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
Adooq's HSP-990 has been cited by 1 publications
  • Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422
  • Chemical Information
    Catalog Num A12850
    M. Wt 379.39
    Formula C20H18FN5O2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 934343-74-5
    Synonyms HSP990, HSP 990, NVP-HSP990
    SMILES CC1=NC(=NC2=C1C(=O)N[C@H](C2)C3=C(C=C(C=C3)F)C4=NC(=CC=C4)OC)N
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
    Targets
    Target Value
    Solubility
    In vitro DMSO 65 mg/mL (171.32 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.36 mL 131.79 mL 263.58 mL
    0.5 mM 5.27 mL 26.36 mL 52.72 mL
    1 mM 2.64 mL 13.18 mL 26.36 mL
    5 mM 0.53 mL 2.64 mL 5.27 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.