Product Data Sheet

FR183998 free base

Catalog No. A12855

main product photo
FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.
Chemical Information
Catalog NumA12855
M. Wt428.34
FormulaC17H19Cl2N5O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.239440-20-1
SynonymsFR-183998, FR 183998
SMILESO=C(C1=CC(C2=C(Cl)SC(Cl)=C2)=CC(C(NCCN(C)C)=O)=C1)NC(N)=N
Biological Activity
DescriptionFR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.
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SHIPPING AND STORAGE
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