Product Data Sheet

Varlitinib tosylate (ASLAN001 tosylate, ARRY-334543 tosylate)

Catalog No. A12868

main product photo
ARRY-543 is a novel, oral ErbB family inhibitor that, unlike approved ErbB inhibitors, targets all members of the ErbB family, including ErbB3, either directly or indirectly, and has potential advantages in treating tumors that signal through multiple ErbB family members.
Chemical Information
Catalog Num A12868
M. Wt 778.15
Formula C36H35ClN6O6S3
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1146629-86-8
Synonyms ARRY543,ARRY 543
SMILES ClC1=CC(NC2=NC=NC3=CC=C(NC4=N[C@H](C)CO4)C=C32)=CC=C1OCC5=NC=CS5.CC6=CC=C(S(O)=O)C=C6.CC7=CC=C(S(O)=O)C=C7
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription ARRY-543 is a novel, oral ErbB family inhibitor that, unlike approved ErbB inhibitors, targets all members of the ErbB family, including ErbB3, either directly or indirectly, and has potential advantages in treating tumors that signal through multiple ErbB family members.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.