Product Data Sheet

AGI-5198 (IDH-C35)

Catalog No. A12902

main product photo
AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.
Chemical Information
Catalog NumA12902
M. Wt462.56
FormulaC27H31FN4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1355326-35-0
SynonymsAGI5198,AGI 5198, IDHC35
SMILESCC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C
Biological Activity
DescriptionAGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.
Targets
TargetValue
Solubility
In vitro (25°C) DMSO22 mg/mL (47.56 mM)
WaterInsoluble
Ethanol13 mg/mL (28.1 mM)
In vivo 0.5% methylcellulose+0.2% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.62 mL108.09 mL216.19 mL
0.5 mM4.32 mL21.62 mL43.24 mL
1 mM2.16 mL10.81 mL21.62 mL
5 mM0.43 mL2.16 mL4.32 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.