Product Data Sheet

Wnt-C59

Catalog No. A12951

main product photo
Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
Adooq's Wnt-C59 has been cited by 1 publications
  • Laksitorini MD, .et al. , Sci Rep, 2019, Dec 23;9(1):19718 PMID: 31873116
  • Chemical Information
    Catalog NumA12951
    M. Wt379.45
    FormulaC25H21N3O
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1243243-89-1
    SynonymsWntC59
    SMILESCC1=NC=CC(=C1)C2=CC=C(C=C2)CC(=O)NC3=CC=C(C=C3)C4=CN=CC=C4
    Biological Activity
    DescriptionWnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO71 mg/mL (187.1 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM26.35 mL131.77 mL263.54 mL
    0.5 mM5.27 mL26.35 mL52.71 mL
    1 mM2.64 mL13.18 mL26.35 mL
    5 mM0.53 mL2.64 mL5.27 mL
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    SHIPPING AND STORAGE
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