Product Data Sheet

LY573636 (Tasisulam)

Catalog No. A13070

main product photo
LY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.
Adooq's LY573636 (Tasisulam) has been cited by 3 publications
  • Yingzheng Xu, .et al. , JCI Insight, 2024, Jun 13:e174746 PMID: 38869957
  • Ting TC, .et al. , Cell Rep, 2019, Nov 5;29(6):1499-1510.e6 PMID: 31693891
  • Ting Han, .et al. , Science, 2017, Apr 28;356(6336). pii: eaal3755 PMID: 28302793
  • Chemical Information
    Catalog NumA13070
    M. Wt415.11
    FormulaC11H6BrCl2NO3S2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.519055-62-0
    SynonymsLY 573636, LY-573636
    SMILESC1=CC(=C(C=C1Cl)Cl)C(=O)NS(=O)(=O)C2=CC=C(S2)Br
    Biological Activity
    DescriptionLY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.
    Targets
    TargetValue
    Solubility
    In vitro DMSO73 mg/mL (175.85 mM)
    WaterInsoluble
    Ethanol73 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM24.09 mL120.45 mL240.9 mL
    0.5 mM4.82 mL24.09 mL48.18 mL
    1 mM2.41 mL12.05 mL24.09 mL
    5 mM0.48 mL2.41 mL4.82 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.