Product Data Sheet

Fosbretabulin disodium (CA4P)

Catalog No. A13081

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Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities.
Adooq's Fosbretabulin disodium (CA4P) has been cited by 1 publications
  • Valeria Sidorenko, .et al. , Sci Rep, 2024, Jul 30;14(1):17513 PMID: 39080306
  • Chemical Information
    Catalog NumA13081
    M. Wt440.29
    FormulaC18H19Na2O8P
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.168555-66-6, 222030-63-9
    Synonyms
    SMILESCOC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)OP(=O)([O-])[O-].[Na+].[Na+]
    Biological Activity
    DescriptionFosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSOInsoluble
    Water25 mg/mL (56.78 mM)
    EthanolInsoluble
    In vivo Saline with a few drops of 5% Na2CO3 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM22.71 mL113.56 mL227.12 mL
    0.5 mM4.54 mL22.71 mL45.42 mL
    1 mM2.27 mL11.36 mL22.71 mL
    5 mM0.45 mL2.27 mL4.54 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.