Product Data Sheet

alpha-Amyloid Precursor Protein Modulator

Catalog No. A13094

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alpha-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas.
Adooq's alpha-Amyloid Precursor Protein Modulator has been cited by 1 publications
  • Shusen Wang, .et al. , Cell, 2024, Oct 31;187(22):6152-6164 PMID: 39326417
  • Chemical Information
    Catalog NumA13094
    M. Wt501.5
    FormulaC27H30F3N3O3
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.497259-23-1
    SynonymsPKC Activator V
    SMILESCC(C)[C@H]1C(=O)N[C@@H](CC2=C(N1C)C=CC(=C2)NC(=O)/C=C/C=C/C3=CC=C(C=C3)C(F)(F)F)CO
    Biological Activity
    Descriptionalpha-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas.
    Targets
    TargetValue
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