Product Data Sheet

Ledipasvir (GS 5885)

Catalog No. A13155

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Ledipasvir is an inhibitor of the hepatitis C virus HCV NS5A protein
Adooq's Ledipasvir (GS 5885) has been cited by 3 publications
  • Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467
  • Sayuri Nitta, .et al. , Scientific Reports, 2019, 9: 5722 PMID: 30952914
  • Sayuri Nitta, .et al. , Sci Rep, 2016, 6: 34652 PMID: 27703205
  • Chemical Information
    Catalog Num A13155
    M. Wt 889
    Formula C49H54F2N8O6
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 1256388-51-8
    Synonyms GS5885, GS-5885
    SMILES CC(C)[C@@H](C(=O)N1CC2(CC2)C[C@H]1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)[C@@H]9[C@H]1CC[C@H](C1)N9C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Ledipasvir is an inhibitor of the hepatitis C virus HCV NS5A protein
    Targets
    Target Value
    Solubility
    In vitro DMSO 93 mg/mL (104.61 mM)
    Water Insoluble
    Ethanol 93 mg/mL (104.61 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 11.25 mL 56.24 mL 112.49 mL
    0.5 mM 2.25 mL 11.25 mL 22.5 mL
    1 mM 1.12 mL 5.62 mL 11.25 mL
    5 mM 0.22 mL 1.12 mL 2.25 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.