Product Data Sheet

AZD1208

Catalog No. A13203

main product photo
AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.
Adooq's AZD1208 has been cited by 7 publications
  • Corbin C Jensen, .et al. , J Cell Biol, 2023, Jun 5;222(6):e202208136 PMID: 37042842
  • Jeremiah J Bearss, .et al. , EMBO Rep, 2021, Apr 7;22(4):e50835 PMID: 33586867
  • Remy J, .et al. , Biochim Biophys Acta Mol Cell Res, 2019, Feb;1866(2):175-189 PMID: 30389373
  • Andrea L. Casillas, .et al. , Clin Cancer Res, 2018, Jan 1; 24(1): 169-180 PMID: 29084916
  • Jin H. Song, .et al. , Mol Cancer Ther, 2018, Dec;17(12):2710-2721 PMID: 30190422
  • Sathish K.R. Padi, .et al. , Oncotarget, 2017, May 2; 8(18): 30199-30216 PMID: 28415816
  • Lim R, .et al. , Mol Hum Reprod, 2017, Jun 1;23(6):428-440 PMID: 28333279
  • Chemical Information
    Catalog NumA13203
    M. Wt379.48
    FormulaC21H21N3O2S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1204144-28-4
    SynonymsAZD 1208, AZD-1208
    SMILESC1C[C@H](CN(C1)C2=C(C=CC=C2/C=C\3/C(=O)NC(=O)S3)C4=CC=CC=C4)N
    Biological Activity
    DescriptionAZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.
    Targets
    TargetValue
    Solubility
    In vitro DMSOWarmed: 70 mg/mL (184.45 mM)
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM26.35 mL131.76 mL263.52 mL
    0.5 mM5.27 mL26.35 mL52.7 mL
    1 mM2.64 mL13.18 mL26.35 mL
    5 mM0.53 mL2.64 mL5.27 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.