Product Data Sheet

AZD1208

Catalog No. A13203

main product photo
AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.
Adooq's AZD1208 has been cited by 7 publications
  • Corbin C Jensen, .et al. , J Cell Biol, 2023, Jun 5;222(6):e202208136 PMID: 37042842
  • Jeremiah J Bearss, .et al. , EMBO Rep, 2021, Apr 7;22(4):e50835 PMID: 33586867
  • Remy J, .et al. , Biochim Biophys Acta Mol Cell Res, 2019, Feb;1866(2):175-189 PMID: 30389373
  • Andrea L. Casillas, .et al. , Clin Cancer Res, 2018, Jan 1; 24(1): 169-180 PMID: 29084916
  • Jin H. Song, .et al. , Mol Cancer Ther, 2018, Dec;17(12):2710-2721 PMID: 30190422
  • Sathish K.R. Padi, .et al. , Oncotarget, 2017, May 2; 8(18): 30199-30216 PMID: 28415816
  • Lim R, .et al. , Mol Hum Reprod, 2017, Jun 1;23(6):428-440 PMID: 28333279
    • Chemical Information
    Catalog Num A13203
    M. Wt 379.48
    Formula C21H21N3O2S
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 1204144-28-4
    Synonyms AZD 1208, AZD-1208
    SMILES C1C[C@H](CN(C1)C2=C(C=CC=C2/C=C\3/C(=O)NC(=O)S3)C4=CC=CC=C4)N
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.
    Targets
    Target Value
    Solubility
    In vitro DMSO Warmed: 70 mg/mL (184.45 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.35 mL 131.76 mL 263.52 mL
    0.5 mM 5.27 mL 26.35 mL 52.7 mL
    1 mM 2.64 mL 13.18 mL 26.35 mL
    5 mM 0.53 mL 2.64 mL 5.27 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.