Product Data Sheet

Ferrostatin-1 (Fer-1)

Catalog No. A13247

main product photo
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
Adooq's Ferrostatin-1 (Fer-1) has been cited by 4 publications
  • Chengzhu Song, .et al. , Food Funct, 2023, Jan 23;14(2):1087-1098 PMID: 36594456
  • Erva Ozkan, .et al. , Life Sci, 2023, Jan 1;312:121222 PMID: 36442526
  • Xueyan Zhang, .et al. , DNA Cell Biol, 2022, Aug;41(8):705-715 PMID: 35687364
  • A Xavier, .et al. , Cell Rep, 2020, May 19;31(7):107667 PMID: 32433976
    • Chemical Information
    Catalog Num A13247
    M. Wt 262.35
    Formula C15H22N2O2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 347174-05-4
    Synonyms Fer1
    SMILES CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO 45 mg/mL (171.52 mM)
    Water Insoluble
    Ethanol 45 mg/mL
    In vivo 2% DMSO+50% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 38.12 mL 190.59 mL 381.17 mL
    0.5 mM 7.62 mL 38.12 mL 76.23 mL
    1 mM 3.81 mL 19.06 mL 38.12 mL
    5 mM 0.76 mL 3.81 mL 7.62 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.