Product Data Sheet

MGL-3196

Catalog No. A13248

main product photo
MGL-3196 is an orally small-molecule liver-directed thyroid hormone receptor agonist designed to increase cholesterol uptake into the liver and increase its metabolism.
Chemical Information
Catalog Num A13248
M. Wt 435.22
Formula C17H12Cl2N6O4
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 920509-32-6
Synonyms MGL3196, MGL 3196
SMILES CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription MGL-3196 is an orally small-molecule liver-directed thyroid hormone receptor agonist designed to increase cholesterol uptake into the liver and increase its metabolism.
Solubility
In vitro DMSO 80 mg/mL (183.81 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.98 mL 114.88 mL 229.77 mL
0.5 mM 4.6 mL 22.98 mL 45.95 mL
1 mM 2.3 mL 11.49 mL 22.98 mL
5 mM 0.46 mL 2.3 mL 4.6 mL
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.