Product Data Sheet

E 64d (Aloxistatin)

Catalog No. A13259

main product photo
E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
Adooq's E 64d (Aloxistatin) has been cited by 4 publications
  • Montserrat Llanses Martinez, .et al. , PLoS Biol, 2024, Dec 12;22(12):e3002930 PMID: 39666682
  • Montserrat Llanses Martinez, .et al. , bioRxiv, 2024, January 14
  • Jason J McDougall, .et al. , Mol Pain, 2021, 17 PMID: 34006144
  • Paudel DB, .et al. , Virology, 2018, Nov;524:127-139 PMID: 30195250
  • Chemical Information
    Catalog NumA13259
    M. Wt342.43
    FormulaC17H30N2O5
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.88321-09-9
    SynonymsE-64d, E64d
    SMILESCCOC(=O)[C@@H]1[C@H](O1)C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C
    Biological Activity
    DescriptionE-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO67 mg/mL (195.66 mM)
    WaterInsoluble
    Ethanol67 mg/mL
    In vivo 2% DMSO+corn oil 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM29.2 mL146.02 mL292.03 mL
    0.5 mM5.84 mL29.2 mL58.41 mL
    1 mM2.92 mL14.6 mL29.2 mL
    5 mM0.58 mL2.92 mL5.84 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.