Product Data Sheet

ETP-46464

Catalog No. A13328

main product photo
ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
Adooq's ETP-46464 has been cited by 1 publications
  • Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458
    • Chemical Information
    Catalog Num A13328
    M. Wt 470.52
    Formula C30H22N4O2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 1345675-02-6
    Synonyms ETP46464, ETP 46464
    SMILES CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
    Targets
    Target Value
    Solubility
    In vitro DMSO 6 mg/mL (12.75 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.25 mL 106.27 mL 212.53 mL
    0.5 mM 4.25 mL 21.25 mL 42.51 mL
    1 mM 2.13 mL 10.63 mL 21.25 mL
    5 mM 0.43 mL 2.13 mL 4.25 mL
    RETURN POLICY
    Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.