Product Data Sheet

Metyrapone

Catalog No. A13363

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Metyrapone is an inhibitor of cytochrome P450-mediated ω/ω-1 hydroxylase activity and CYP11B1.
Adooq's Metyrapone has been cited by 2 publications
  • Vera-Chang MN, .et al. , Proc Natl Acad Sci U S A, 2018, Dec 10. pii: 201811695 PMID: 30530669
  • Tea J, .et al. , J Exp Biol, 2018, Dec 10. pii: jeb.194894 PMID: 30530837
  • Chemical Information
    Catalog Num A13363
    M. Wt 226.27
    Formula C14H14N2O
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 54-36-4
    Synonyms
    SMILES CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Metyrapone is an inhibitor of cytochrome P450-mediated ω/ω-1 hydroxylase activity and CYP11B1.
    Solubility
    In vitro DMSO 44 mg/mL (194.45 mM)
    Ethanol <1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 44.19 mL 220.97 mL 441.95 mL
    0.5 mM 8.84 mL 44.19 mL 88.39 mL
    1 mM 4.42 mL 22.1 mL 44.19 mL
    5 mM 0.88 mL 4.42 mL 8.84 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.