Product Data Sheet

Z-DEVD-FMK

Catalog No. A13503

main product photo
Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.

Adooq's Z-DEVD-FMK has been cited by 6 publications
  • Megumi Andoh, .et al. , Nat Commun, 2025, Jan 22;16(1):918 PMID: 39843445
  • Geoffrey Canet, .et al. , Res Sq, 2024, May 14:rs.3.rs-4384494 PMID: 38798432
  • Roi Ankawa, .et al. , Dev Cell, 2021, Jul 12;56(13):1900-1916 PMID: 34197726
  • Yosefzon Y, .et al. , Mol Cell, 2018, May 17;70(4):573-587.e4 PMID: 29775577
  • Akashi E, .et al. , Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026
  • Wenquan Liang, .et al. , Sci Rep, 2016, 6: 38267 PMID: 27905569
  • Chemical Information
    Catalog NumA13503
    M. Wt668.66
    FormulaC30H41FN4O12
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.210344-95-9
    SynonymsCaspase-3 Inhibitor
    SMILESO=C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)[C@H](CCC(OC)=O)NC([C@H](CC(OC)=O)NC(OCC1=CC=CC=C1)=O)=O
    Biological Activity
    DescriptionZ-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO98 mg/mL (146.56 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 2% DMSO+30% PEG 400+5% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM14.96 mL74.78 mL149.55 mL
    0.5 mM2.99 mL14.96 mL29.91 mL
    1 mM1.5 mL7.48 mL14.96 mL
    5 mM0.3 mL1.5 mL2.99 mL
    RETURN POLICY
    Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.