Product Data Sheet

Pamapimod (R-1503)

Catalog No. A13551

main product photo
Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.
Chemical Information
Catalog Num A13551
M. Wt 406.38
Formula C19H20F2N4O4
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 449811-01-2
Synonyms R 1503, R1503, R-1503, Ro 4402257, Ro4402257, Ro-4402257
SMILES CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.
Targets
Target Value
Solubility
In vitro DMSO 70 mg/mL (172.25 mM)
Water Insoluble
Ethanol 24 mg/mL (59.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.61 mL 123.04 mL 246.08 mL
0.5 mM 4.92 mL 24.61 mL 49.22 mL
1 mM 2.46 mL 12.3 mL 24.61 mL
5 mM 0.49 mL 2.46 mL 4.92 mL
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.