Product Data Sheet

SAG

Catalog No. A13627

main product photo
SAG is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 uM).
Adooq's SAG has been cited by 1 publications
  • Mark van den Hurk, .et al. , NPJ Parkinsons Dis, 2022, Oct 18;8(1):134 PMID: 36258029
  • Chemical Information
    Catalog NumA13627
    M. Wt490.1
    FormulaC28H28ClN3OS
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.912545-86-9
    SynonymsSmoothened Agonist
    SMILESCNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl
    Biological Activity
    DescriptionSAG is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 uM).
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