Product Data Sheet

JW-642

Catalog No. A13774

main product photo
JW-642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.
Chemical Information
Catalog NumA13774
M. Wt462.4
FormulaC21H20F6N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1416133-89-5
SynonymsJW 642, JW642
SMILESO=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(CC2=CC=CC(OC3=CC=CC=C3)=C2)CC1
Biological Activity
DescriptionJW-642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.
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