Product Data Sheet

GO6983

Catalog No. A13790

main product photo
GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
Adooq's GO6983 has been cited by 1 publications
  • Kouki Kawakami, .et al. , Nat Commun, 2022, 13: 487 PMID: 35078997
  • Chemical Information
    Catalog Num A13790
    M. Wt 442.51
    Formula C26H26N4O3
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 133053-19-7
    Synonyms Go-6983, Go 6983
    SMILES CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO 55 mg/mL (124.29 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.6 mL 112.99 mL 225.98 mL
    0.5 mM 4.52 mL 22.6 mL 45.2 mL
    1 mM 2.26 mL 11.3 mL 22.6 mL
    5 mM 0.45 mL 2.26 mL 4.52 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.