Product Data Sheet

4μ8C

Catalog No. A13803

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4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.

Adooq's 4μ8C has been cited by 1 publications
  • Gideon Ong, .et al. , Cell Death Dis, 2024, Apr 18;15(4):276 PMID: 38637497
  • Chemical Information
    Catalog NumA13803
    M. Wt204.18
    FormulaC11H8O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.14003-96-4
    Synonyms
    SMILESCC1=CC(=O)OC2=C1C=CC(=C2C=O)O
    Biological Activity
    Description4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO17 mg/mL (83.26 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 0.4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM48.98 mL244.88 mL489.76 mL
    0.5 mM9.8 mL48.98 mL97.95 mL
    1 mM4.9 mL24.49 mL48.98 mL
    5 mM0.98 mL4.9 mL9.8 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.