Product Data Sheet

Marizomib (NPI-0052, salinosporamide A)

Catalog No. A13853

main product photo
Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity.
Adooq's Marizomib (NPI-0052, salinosporamide A) has been cited by 1 publications
  • Tarantelli C, .et al. , Clin Cancer Res, 2018, Jan 1;24(1):120-129 PMID: 29066507
    • Chemical Information
    Catalog Num A13853
    M. Wt 313.77
    Formula C15H20ClNO4
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 437742-34-2
    Synonyms ML 858, Marizomib, NPI 0052, Salinosporamide A
    SMILES C[C@]12[C@H](C(=O)N[C@]1(C(=O)O2)[C@H]([C@H]3CCCC=C3)O)CCCl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity.
    Solubility
    In vitro DMSO 59 mg/mL (188.02 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.87 mL 159.35 mL 318.7 mL
    0.5 mM 6.37 mL 31.87 mL 63.74 mL
    1 mM 3.19 mL 15.94 mL 31.87 mL
    5 mM 0.64 mL 3.19 mL 6.37 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.