Product Data Sheet

Obeticholic Acid

Catalog No. A13866

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Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM
Adooq's Obeticholic Acid has been cited by 2 publications
  • Wonsik Jung, .et al. , Adv Mater, 2024, Jun;36(24):e2305830 PMID: 38459924
  • Tomasz Kostrzewski, .et al. , Hepatol Commun, 2019, 13 November
  • Chemical Information
    Catalog NumA13866
    M. Wt420.63
    FormulaC26H44O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.459789-99-2
    SynonymsINT-747, 6-ECDCA
    SMILESCC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)C)O
    Biological Activity
    DescriptionObeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM
    Targets
    TargetValue
    Solubility
    In vitro DMSO76 mg/mL (180.68 mM)
    WaterInsoluble
    EthanolWarmed: 76 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM23.77 mL118.87 mL237.74 mL
    0.5 mM4.75 mL23.77 mL47.55 mL
    1 mM2.38 mL11.89 mL23.77 mL
    5 mM0.48 mL2.38 mL4.75 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.