Product Data Sheet
Dendrotoxin-I
Catalog No. A13926
Dendrotoxin-I (DTX-I) is a potent inhibitor of voltage-gated potassium channels, specifically targeting the KV1.1, KV1.2, and KV1.6 subunits with IC50 values ranging from 0.13 to 50 nM. This neurotoxin exhibits significant biological activity that can influence neuronal excitability and synaptic transmission. Dendrotoxin-I is primarily utilized in research applications related to cancer and neurobiology, providing insights into ion channel function and their roles in disease mechanisms.
Chemical Information
| Catalog Num | A13926 |
|---|---|
| M. Wt | 7149.24 |
| Formula | C312H491N99O83S6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 107950-33-4 |
| Synonyms | DTX-I |
| SMILES |
Biological Activity
| Description | Dendrotoxin-I (DTX-I) is a potent inhibitor of voltage-gated potassium channels, specifically targeting the KV1.1, KV1.2, and KV1.6 subunits with IC50 values ranging from 0.13 to 50 nM. This neurotoxin exhibits significant biological activity that can influence neuronal excitability and synaptic transmission. Dendrotoxin-I is primarily utilized in research applications related to cancer and neurobiology, providing insights into ion channel function and their roles in disease mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
