Product Data Sheet

BAPTA/AM

Catalog No. A14023

main product photo
BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.
Adooq's BAPTA/AM has been cited by 5 publications
  • Jiunn-Chang Lin, .et al. , Toxicol Appl Pharmacol, 2023, Jul 15;471:116568 PMID: 37245555
  • Liying Wu, .et al. , Phytother Res, 2022, Feb;36(2):938-950 PMID: 35076979
  • Shichen Xu, .et al. , Cell Signal, 2020, Aug 6;75:109733 PMID: 32771398
  • Miho Akimoto, .et al. , Cell Death Dis, 2018, Aug; 9(8): 804 PMID: 30038429
  • Zhang L, .et al. , Medicine (Baltimore), 2018, Jun;97(24):e11095 PMID: 29901626
    • Chemical Information
    Catalog Num A14023
    M. Wt 764.68
    Formula C34H40N2O18
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 126150-97-8
    Synonyms BAPTA-AM, BAPTA AM
    SMILES CC(=O)OCOC(=O)CN(CC(=O)OCOC(=O)C)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.
    Solubility
    In vitro DMSO 19 mg/mL (24.84 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 13.08 mL 65.39 mL 130.77 mL
    0.5 mM 2.62 mL 13.08 mL 26.15 mL
    1 mM 1.31 mL 6.54 mL 13.08 mL
    5 mM 0.26 mL 1.31 mL 2.62 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.