Product Data Sheet

Sivelestat sodium salt

Catalog No. A14073

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Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
Adooq's Sivelestat sodium salt has been cited by 1 publications
  • Shasha He, .et al. , Nature Biomedical Engineering, 2023, 7: 281-297
  • Chemical Information
    Catalog NumA14073
    M. Wt456.44
    FormulaC20H21N2NaO7S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.150374-95-1
    SynonymsONO-5046
    SMILESCC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
    Biological Activity
    DescriptionSivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
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