Product Data Sheet

BV-6

Catalog No. A14231

main product photo
BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.

Adooq's BV-6 has been cited by 1 publications
  • Aneri Shah, .et al. , Cancers (Basel), 2020, Aug 5;12(8):E2188 PMID: 32764479
  • Chemical Information
    Catalog Num A14231
    M. Wt 1205.57
    Formula C70H96N10O8
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 1001600-56-1
    Synonyms BV6
    SMILES C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)NCCCCCCNC(=O)[C@H](C(C5=CC=CC=C5)C6=CC=CC=C6)NC(=O)[C@@H]7CCCN7C(=O)[C@H](C8CCCCC8)NC(=O)[C@H](C)NC)NC
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.
    Solubility
    In vitro DMSO 96 mg/mL (79.62 mM)
    Water 24 mg/mL (19.9 mM)
    Ethanol Warmed: 96 mg/mL (79.62 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 8.29 mL 41.47 mL 82.95 mL
    0.5 mM 1.66 mL 8.29 mL 16.59 mL
    1 mM 0.83 mL 4.15 mL 8.29 mL
    5 mM 0.17 mL 0.83 mL 1.66 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.