Product Data Sheet

MG149

Catalog No. A14267

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MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 uM and 47 uM for Tip60 and MOF.
Adooq's MG149 has been cited by 1 publications
  • Thibaud Reyser, .et al. , Pharmaceutics, 2023, Oct 10;15(10):2440 PMID: 37896200
  • Chemical Information
    Catalog NumA14267
    M. Wt340.46
    FormulaC22H28O3
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1243583-85-8
    SynonymsMG 149,MG-149
    SMILESCCCCCCCC1=CC=C(C=C1)CCC2=C(C(=CC=C2)O)C(=O)O
    Biological Activity
    DescriptionMG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 uM and 47 uM for Tip60 and MOF.
    Targets
    TargetValue
    Solubility
    In vitro DMSO63 mg/mL (185.03 mM)
    WaterInsoluble
    Ethanol63 mg/mL (185.03 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM29.37 mL146.86 mL293.72 mL
    0.5 mM5.87 mL29.37 mL58.74 mL
    1 mM2.94 mL14.69 mL29.37 mL
    5 mM0.59 mL2.94 mL5.87 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.