Product Data Sheet

Sitagliptin

Catalog No. A14377

main product photo
Sitagliptin is an oral antihyperglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.
Adooq's Sitagliptin has been cited by 2 publications
  • Hae Jin Kim, .et al. , Korean J Physiol Pharmacol, 2018, Nov; 22(6): 713-719 PMID: 30402032
  • Chintan N. Koyani, .et al. , Front Physiol, 2018, 9: 1622 PMID: 30487758
  • Chemical Information
    Catalog NumA14377
    M. Wt407.31
    FormulaC16H15F6N5O
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.486460-32-6
    SynonymsMK-0431, MK 0431, MK0431
    SMILESC1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
    Biological Activity
    DescriptionSitagliptin is an oral antihyperglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.
    Solubility
    In vitro DMSO79 mg/mL (193.95 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM24.55 mL122.76 mL245.51 mL
    0.5 mM4.91 mL24.55 mL49.1 mL
    1 mM2.46 mL12.28 mL24.55 mL
    5 mM0.49 mL2.46 mL4.91 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.