Product Data Sheet

SBE 13 HCl

Catalog No. A14426

main product photo
SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).
Chemical Information
Catalog NumA14426
M. Wt479.4
FormulaC24H27ClN2O4.HCl
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1052532-15-6
SynonymsSBE-13, SBE 13
SMILESCOC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl
Biological Activity
DescriptionSBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).
Targets
TargetValue
Solubility
In vitro DMSO90 mg/mL (187.73 mM)
WaterInsoluble
EthanolInsoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM20.86 mL104.3 mL208.59 mL
0.5 mM4.17 mL20.86 mL41.72 mL
1 mM2.09 mL10.43 mL20.86 mL
5 mM0.42 mL2.09 mL4.17 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.