Product Data Sheet

Cimifugin

Catalog No. A14456

main product photo
Cimifugin is an anti-allergic agent derived from the herb Cimicifuga racemosa. It exhibits properties that suppress allergic inflammation by modulating key factors derived from epithelial cells and regulating tight junction integrity. Additionally, Cimifugin demonstrates a capacity to reduce the migration and chemotaxis of RAW264.7 macrophage cells while inhibiting the release of inflammatory mediators and the activation of MAPK and NF-κB signaling pathways triggered by LPS. This compound is valuable for research into mechanisms of allergic responses and inflammatory conditions.
Chemical Information
Catalog NumA14456
M. Wt306.31
FormulaC16H18O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.37921-38-3
SynonymsCimitin
SMILESO=C1C=C(CO)OC2=CC(O[C@H](C(C)(O)C)C3)=C3C(OC)=C12
Biological Activity
DescriptionCimifugin is an anti-allergic agent derived from the herb Cimicifuga racemosa. It exhibits properties that suppress allergic inflammation by modulating key factors derived from epithelial cells and regulating tight junction integrity. Additionally, Cimifugin demonstrates a capacity to reduce the migration and chemotaxis of RAW264.7 macrophage cells while inhibiting the release of inflammatory mediators and the activation of MAPK and NF-κB signaling pathways triggered by LPS. This compound is valuable for research into mechanisms of allergic responses and inflammatory conditions.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.