Cimifugin
Catalog No. A14456

Cimifugin is an anti-allergic agent derived from the herb Cimicifuga racemosa. It exhibits properties that suppress allergic inflammation by modulating key factors derived from epithelial cells and regulating tight junction integrity. Additionally, Cimifugin demonstrates a capacity to reduce the migration and chemotaxis of RAW264.7 macrophage cells while inhibiting the release of inflammatory mediators and the activation of MAPK and NF-κB signaling pathways triggered by LPS. This compound is valuable for research into mechanisms of allergic responses and inflammatory conditions.
Chemical Information
| Catalog Num | A14456 |
|---|---|
| M. Wt | 306.31 |
| Formula | C16H18O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 37921-38-3 |
| Synonyms | Cimitin |
| SMILES | O=C1C=C(CO)OC2=CC(O[C@H](C(C)(O)C)C3)=C3C(OC)=C12 |
Biological Activity
| Description | Cimifugin is an anti-allergic agent derived from the herb Cimicifuga racemosa. It exhibits properties that suppress allergic inflammation by modulating key factors derived from epithelial cells and regulating tight junction integrity. Additionally, Cimifugin demonstrates a capacity to reduce the migration and chemotaxis of RAW264.7 macrophage cells while inhibiting the release of inflammatory mediators and the activation of MAPK and NF-κB signaling pathways triggered by LPS. This compound is valuable for research into mechanisms of allergic responses and inflammatory conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


