Product Data Sheet
Xylitol
Catalog No. A14546
Xylitol is a polyol classified as a sugar alcohol, known for its inhibitory effects on cancer cell proliferation. It induces autophagy and promotes cell death in A549 lung cancer cells by activating the autophagy signaling pathway, as indicated by increased levels of LC3-II and Atg5-Atg12. Additionally, Xylitol reduces acetaldehyde production by Candida species, thereby mitigating their carcinogenic potential. In vivo studies demonstrate that Xylitol modifies gut microbiota in mice, potentially enhancing cholesterol accumulation, upregulating hepatic ChREBP, and inhibiting tumor growth in the B16F10 melanoma model.
Chemical Information
| Catalog Num | A14546 |
|---|---|
| M. Wt | 152.15 |
| Formula | C5H12O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 87-99-0 |
| Synonyms | Xylite |
| SMILES | OC[C@@H](O)[C@H](O)[C@@H](O)CO |
Biological Activity
| Description | Xylitol is a polyol classified as a sugar alcohol, known for its inhibitory effects on cancer cell proliferation. It induces autophagy and promotes cell death in A549 lung cancer cells by activating the autophagy signaling pathway, as indicated by increased levels of LC3-II and Atg5-Atg12. Additionally, Xylitol reduces acetaldehyde production by Candida species, thereby mitigating their carcinogenic potential. In vivo studies demonstrate that Xylitol modifies gut microbiota in mice, potentially enhancing cholesterol accumulation, upregulating hepatic ChREBP, and inhibiting tumor growth in the B16F10 melanoma model. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
