Product Data Sheet

Guanfacine hydrochloride

Catalog No. A15098

main product photo
Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors.
Chemical Information
Catalog Num A15098
M. Wt 282.55
Formula C9H10Cl3N3O
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 29110-48-3
Synonyms Guanfacine, Tenex, Intuniv
SMILES C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors.
Targets
Target Value
Solubility
In vitro DMSO 48 mg/mL (169.88 mM)
Water 26 mg/mL (92.01 mM)
Ethanol 48 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.39 mL 176.96 mL 353.92 mL
0.5 mM 7.08 mL 35.39 mL 70.78 mL
1 mM 3.54 mL 17.7 mL 35.39 mL
5 mM 0.71 mL 3.54 mL 7.08 mL
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.