Product Data Sheet

NB-598 Maleate

Catalog No. A15180

main product photo
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.
Adooq's NB-598 Maleate has been cited by 3 publications
  • Gia-Buu Tran, .et al. , Cancer Res, 2023, Apr 14;CAN-22-3450 PMID: 37057874
  • Weber RA, .et al. , Mol Cell, 2020, Feb 6;77(3):645-655 PMID: 31983508
  • Garcia-Bermudez J, .et al. , Nature, 2019, Feb 13 PMID: 30760928
    • Chemical Information
    Catalog Num A15180
    M. Wt 565.74
    Formula C31H35NO5S2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 155294-62-5, 136719-26-1
    Synonyms NB598 Maleate, NB 598 Maleate
    SMILES CCN(C/C=C/C#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3.C(=C\C(=O)O)\C(=O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.