Product Data Sheet

b-AP15 (NSC 687852)

Catalog No. A15391

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NSC 687852 is an inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5), two proteasome-associated DUBs.
Adooq's b-AP15 (NSC 687852) has been cited by 1 publications
  • Anurag Rathore, .et al. , Sci Rep, 2020, 10: 5350 PMID: 32210344
  • Chemical Information
    Catalog NumA15391
    M. Wt419.39
    FormulaC22H17N3O6
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1009817-63-3
    Synonymsb-AP15
    SMILESC=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1
    Biological Activity
    DescriptionNSC 687852 is an inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5), two proteasome-associated DUBs.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSOWarmed: 42 mg/mL (100.14 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 4% DMSO+corn oil 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM23.84 mL119.22 mL238.44 mL
    0.5 mM4.77 mL23.84 mL47.69 mL
    1 mM2.38 mL11.92 mL23.84 mL
    5 mM0.48 mL2.38 mL4.77 mL
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