Product Data Sheet
Desmethoxyyangonin
Catalog No. A15600
Desmethoxyyangonin is a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 0.123 µM. This kavalactone, derived from the Piper methysticum plant, exhibits notable anti-inflammatory properties through the inhibition of Jak2/STAT3 and IKK signaling pathways. Additionally, Desmethoxyyangonin plays a role in inducing CYP3A23 expression and contributes to skeletal muscle relaxation, making it a valuable tool for research in neuropharmacology and inflammation.
Chemical Information
| Catalog Num | A15600 |
|---|---|
| M. Wt | 228.24 |
| Formula | C14H12O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 15345-89-8 |
| Synonyms | Demethoxyyangonin; 5,6-Dehydrokavain |
| SMILES | O=C1C=C(OC)C=C(/C=C/C2=CC=CC=C2)O1 |
Biological Activity
| Description | Desmethoxyyangonin is a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 0.123 µM. This kavalactone, derived from the Piper methysticum plant, exhibits notable anti-inflammatory properties through the inhibition of Jak2/STAT3 and IKK signaling pathways. Additionally, Desmethoxyyangonin plays a role in inducing CYP3A23 expression and contributes to skeletal muscle relaxation, making it a valuable tool for research in neuropharmacology and inflammation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
