Product Data Sheet
Ginsenoside Rg5
Catalog No. A15613
Ginsenoside Rg5 is a potent IGF-1R agonist primarily derived from Red ginseng. It functions by competing at the IGF-1 binding site on IGF-1R, effectively obstructing IGF-1's interaction and exhibiting an IC50 of approximately 90 nM. Additionally, Ginsenoside Rg5 downregulates COX-2 mRNA expression through inhibition of NF-κB p65 DNA binding activities, making it valuable for research into inflammation and metabolic regulation.
Chemical Information
| Catalog Num | A15613 |
|---|---|
| M. Wt | 767.00 |
| Formula | C42H70O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 186763-78-0 |
| Synonyms | |
| SMILES | C[C@@]([C@@]12C)(CC[C@@]3([H])C4(C)C)[C@@](C[C@@H](O)[C@]1([H])[C@@H](/C(C)=C/C/C=C(C)\C)CC2)([H])[C@]3(CC[C@@H]4O[C@@](O[C@H](CO)[C@@H](O)[C@@H]5O)([H])[C@@H]5O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)C |
Biological Activity
| Description | Ginsenoside Rg5 is a potent IGF-1R agonist primarily derived from Red ginseng. It functions by competing at the IGF-1 binding site on IGF-1R, effectively obstructing IGF-1's interaction and exhibiting an IC50 of approximately 90 nM. Additionally, Ginsenoside Rg5 downregulates COX-2 mRNA expression through inhibition of NF-κB p65 DNA binding activities, making it valuable for research into inflammation and metabolic regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
