Product Data Sheet
Apigenin-7-glucuronide
Catalog No. A15642
Apigenin-7-glucuronide is a potent inhibitor of Matrix Metalloproteinases (MMP), demonstrating IC50 values of 12.87 µM for MMP-3, 22.39 µM for MMP-8, 17.52 µM for MMP-9, and 0.27 µM for MMP-13. This compound's ability to modulate MMP activity makes it valuable for investigations into extracellular matrix regulation, tissue remodeling, and various inflammatory conditions. Researchers may utilize Apigenin-7-glucuronide in studies aiming to explore therapeutic interventions in diseases associated with MMP dysregulation.
Chemical Information
| Catalog Num | A15642 |
|---|---|
| M. Wt | 446.36 |
| Formula | C21H18O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 29741-09-1 |
| Synonyms | Apigenin 7-O-glucuronide |
| SMILES | O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC(O)=C3C(C=C(C4=CC=C(O)C=C4)OC3=C2)=O |
Biological Activity
| Description | Apigenin-7-glucuronide is a potent inhibitor of Matrix Metalloproteinases (MMP), demonstrating IC50 values of 12.87 µM for MMP-3, 22.39 µM for MMP-8, 17.52 µM for MMP-9, and 0.27 µM for MMP-13. This compound's ability to modulate MMP activity makes it valuable for investigations into extracellular matrix regulation, tissue remodeling, and various inflammatory conditions. Researchers may utilize Apigenin-7-glucuronide in studies aiming to explore therapeutic interventions in diseases associated with MMP dysregulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
