Product Data Sheet

Xanthohumol

Catalog No. A15919

main product photo
Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects.
Adooq's Xanthohumol has been cited by 1 publications
  • Rachel Clark, .et al. , Mol Carcinog, 2026, Apr;65(4):508-522 PMID: 41664946
  • Chemical Information
    Catalog NumA15919
    M. Wt354.4
    FormulaC21H22O5
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.6754-58-1
    Synonyms
    SMILESCC(=CCC1=C(C=C(C(=C1O)C(=O)C=CC2=CC=C(C=C2)O)OC)O)C
    Biological Activity
    DescriptionXanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO67 mg/mL (189.05 mM)
    WaterInsoluble
    Ethanol67 mg/mL (189.05 mM)
    In vivo 0.05% (w+w) xanthohumol powder in diet, or suspended in ethanol (2.5 mg+mL) 12 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM28.22 mL141.08 mL282.17 mL
    0.5 mM5.64 mL28.22 mL56.43 mL
    1 mM2.82 mL14.11 mL28.22 mL
    5 mM0.56 mL2.82 mL5.64 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.